Aminopyridines and similarly acting drugs effects on nerves, muscles, and synapses : proceedings of a IUPHAR satellite symposium in conjunction with the 8th International Congress of Pharmacology, Paris, France, July 27-29, 1981

Cover of: Aminopyridines and similarly acting drugs |

Published by Pergamon Press in Oxford [Oxfordshire], New York .

Written in English

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Subjects:

  • Aminopyridines -- Physiological effect -- Congresses.,
  • Neuropharmacology -- Congresses.,
  • Aminopyridines -- Pharmacodynamics -- Congresses.,
  • Nervous system -- Drug effects -- Congresses.,
  • Muscles -- Drug effects -- Congresses.,
  • Neural transmission -- Drug effects -- Congresses.

Edition Notes

Includes bibliographies and index.

Book details

Statementeditors, P. Lechat, S. Thesleff, W.C. Bowman ; organizing committee, Lemeignan, J. Molgo.
SeriesAdvances in the biosciences ;, v. 35
ContributionsLechat, P., Thesleff, S., Bowman, W. C., International Union of Pharmacology., International Congress of Pharmacology (8th : 1981 : Paris, France)
Classifications
LC ClassificationsRM666.A465 A44 1982
The Physical Object
Paginationxvi, 346 p. :
Number of Pages346
ID Numbers
Open LibraryOL3481207M
ISBN 100080280005
LC Control Number82000533

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Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses Proceedings of a IUPHAR Satellite Symposium in Conjunction with the 8th International Congress of Pharmacology, Paris, France, July 27–29, Book •   Description Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth International Congress of Pharmacology held in Paris, France on JulyBook Edition: 1.

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Aminopyridines and Similarly ActiBrand: Elsevier Science. Aminopyridines and similarly acting drugs. Oxford [Oxfordshire] ; New York: Pergamon Press, (OCoLC) Online version: Aminopyridines and similarly acting drugs. Oxford [Oxfordshire] ; New York: Pergamon Press, (OCoLC) Material Type: Conference publication: Document Type: Book: All Authors / Contributors.

Electronic books Conference papers and proceedings Congresses: Additional Physical Format: Print version: Aminopyridines and similarly acting drugs. Oxford [Oxfordshire] ; New York: Pergamon Press, (DLC) (OCoLC) Material Type: Conference publication, Document, Internet resource: Document Type: Internet Resource, Computer File.

Book contents; Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses. Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses. Proceedings of a IUPHAR Satellite Symposium in Conjunction with the 8th International Congress of Pharmacology, Paris, France, July 27–29, Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth International Congress of Pharmacology held in Paris, France on JulyThe book contains papers on the effects of aminopyridines on ionic currents in excitable.

Dunant Y, Clostre F, Jones GJ, Loctin F, Muller D () Aminopyridines as a tool to investigate the mechanism of acetylcholine release at the nerve electroplaque junction. Aminopyridines and similarly acting drugs book Lechat P, Thesleff S, Bowman WC (eds) Aminopyridines and similarly acting drugs: effects on nerves, muscles and synapses.

Advances in the Biosciences, vol Agoston S, Aminopyridines and similarly acting drugs book DRA, Sia RL () Therapeutic applications of 4-aminopyridine in anaesthesia. In: Lechat P, Thesleff S, Bowman WC (eds) Aminopyridines and similarly acting drugs.

Pergamon, Oxford Google Scholar. Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses: Proceedings of a IUPHAR Satellite Symposium in Conjunction with the 8th International Congress of Pharmacology, Paris, France, JulyAminopyridines aminopyridines: • Complete toxicological characterization, including histopathology, in a 2-year carcinogenesis bioassay of 2-aminopyridine.

• Evaluation of 3- and 4-aminopyridine in short-term mechanistic studies to characterize the similarities and differences among this class of chemicals. A.S. Tung, B.W. Brandom, in Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses, Publisher Summary.

4AP reversal of morphine analgesia has been assessed because while morphine sulfate (MS) inhibits the release of neurotransmitters involved with pain transmission, 4AP enhances calcium-dependent neurotransmitter release. 4AP has been used.

Aminopyridines. and. Similarly. Acting. Drugs. Advances. the. Biosciences. Vol. the wealth of potentially offending drug classes, and their potential for reversibility, all. Gibb M, Marshall IG, Bowman WC. Increased tetanic fade produced by 3,4 diaminopyridine in the presence of neuromuscular blocking agents.

In: Aminopyridines and similarly acting drugs: effects on nerves, muscles and synapses. Eds Lechat P et al. Advances in the Biosciencesvol 3 5, Pergamon, Oxford, p Google Scholar. In Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses, Dr. Lewis: The credit for our use of 3,4-diaminopyridine belongs to Professor Thesleff.

It is my hope that clinical trials in human patients will shift to the use of 3,4-diaminopyridine. Regarding Dr. Bowman's question I absolutely agree with your comments. Drug Research Related Books SoS C-1 Building Blocks in Organic Synthesis SoS Multicomponent Reactions SoS Cross Coupling and Heck-Type Reactions SoS Asymmetric Organocatalysis SoS Water in Organic Synthesis Aminopyridines and Similarly Acting Drugs.

Pergamon; Oxford: 4-Aminopyridine (4-AP, fampridine, dalfampridine) is an organic compound with the chemical formula C 5 H 4 N–NH molecule is one of the three isomeric amines of is used as a research tool in characterizing subtypes of the potassium has also been used as a drug, to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of.

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The application of fluctuation analysis to conduction processes in excitable membranes has developed rapidly since the early work of Derksen and Verveen () on the node of Ranvier.

First. A copper-catalyzed 1,2-diol amination at the electron-rich C-5 position of unprotected 2-amino/2-hydroxyhalopyridine provided excellent yields. Selective amination preferably at C-5 in 2-bromoiodopyridine was achieved under the same conditions. The selective, generally mild and.

Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses - Satellite Symposium Proceedings (Advances in the Biosciences S.) Lechat, P., Thesleff, S. & Bowman, W.C. (Ed.) Published by Pergamon (). A method for preparation of a new stable Cu(I) catalyst supported on weakly acidic polyacrylate resin without additional stabilizing ligands is described.

A simple and efficient methodology for Ullmann Cu(I) catalyzed C-N cross coupling reactions using this original catalyst is reported. Coupling reactions of 4-chloropyridinium chloride with anilines containing electron donating (EDG) or. Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth International Congress of Pharmacology held in Paris, France on July().

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por. Physiotherapy Essentials. A facile and selective synthesis of N-substituted 2-aminopyridines is accomplished via microwave-assisted multi-component reactions controlled by the basicity of amine and the nature of solvent.

aminopyridines @ concn above 1x molar caused contractions of guinea pig ileum. aminopyridines may act on cholinergic nerves in ileum, causing incr release of acetylcholine by facilitating calcium movement, not blocking potassium conductance. Introduction. Aminopyridines such as 4-aminopyridine (4-AP) 3 and 3,4-diaminopyridine (3,4-DAP) are widely used as voltage-activated K + (Kv) channel blockers and can improve neuromuscular function in patients with multiple sclerosis (), spinal cord injury (), myasthenia gravis (), or Lambert-Eaton syndrome (4, 5).The classical view is that the beneficial effect of 4-AP results from.

Abstract. The exchange of information between a cell and its environment is frequently mediated by ionic movements through the plasma membrane. The physiology of sea urchin sperm is a representative case in which this phenomenon occurs.

Daniel, Pharmacology of Adrenergic, Cholinergic, and Drugs Acting on Other Receptors in Gastrointestinal Muscle, Mediators and Drugs in Gastrointestinal Motility II, /_9, (), (). Author(s): Lechat,P; Thesleff,S(Stephen); Bowman,W C; International Union of Pharmacology.; International Congress of Pharmacology,(8th: Tokyo, Japan.

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Effects of Aminopyridines in Avian Muscular Dystrophy. Pharmacology of Neuromuscular Function, Second Edition provides information pertinent to drugs that affect membrane potentials of the conduction of action potentials in nerve endings and muscle fibers.

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In this best-selling textbook in psychiatry for over   Of these classes of drugs, aminopyridines, in particular 3,4-diaminopyridine (3,4-DAP), has shown promise due to its agonistic effect on neurotransmitter release through K v channel blockade.

11 The aminopyridines, 3,4-DAP along with 4-aminopyridine (4-AP) facilitate recovery of neuromuscular action potential post botulism intoxication by. Background: A new approach to the treatment of COPD includes controlling inflammation because of its important role in exacerbation of the disease.

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General description 2-Aminopyridine is a basic building block of several heterocyclic compounds and Schiff bases. Application 2-Aminopyridine (2AP) is a derivatizing agent which can be used as a fluorescent label for oligosaccharide detection, chromatographic separation, fluorometric or mass spectrometric analysis.

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